Debiopharm Group™ and Affinium Pharmaceuticals, a Canadian company focusing on the development of a platform of novel, targeted narrow-spectrum antibacterial therapeutics, announced the acquisition by Debiopharm of Affinium’s clinical and preclinical assets as well as its technology platform.
The clinical assets include AFN-1252, a FabI inhibitor designated by the FDA as a Qualified Infectious Disease Product (QIDP) which has successfully completed a Phase 2a study for the treatment of acute bacterial skin and skin structure infections (ABSSSI), and its prodrug AFN-1720, currently in Phase 1 clinical development. Both compounds are highly potent agents that are selectively active against all Staphylococcus species and strains tested thus far (5400 strains) including all known resistant strains such as methicillin-resistant S. aureus (MRSA) and vancomycin-intermediate S. aureus (VISA)…